Sen. Lindsey Graham (R-S.C.) accused President Obama of "turning his agenda over to the most liberal people in the House," and pointed out that few Democrats are campaigning on the Democratic health-care bill. "Most Democrats in swing states are running against Nancy Pelosi and against the Obama takeover of most of society," Graham said. The South Carolina Republican predicted that there will be more bipartisanship in 2011, particularly on extending the Bush-era tax cuts. He defended his friend, Sen. John McCain (R-Ariz.), who took the unusual step of harshly denouncing a Senate colleague -- Sen. Barbara Boxer (D-Calif.) -- at a recent campaign rally for Carly Fiorina. "I think John is reacting to an agenda that he thinks has really been overreaching," Graham said. "It is different. The Senate is different now."